Computer use has become necessary and an integral part of our daily life, especially after the the COVID-19 outbreak. For workers and students, restriction on face-to-face interaction has shifted towards online platform as an alternative. Online meetings and lectures have become our routine practice. However, prolong and improper use of computer may contribute to work-related musculoskeletal disorders (WRMSD). Hence, this course aims to introduce basic office ergonomics and risk factors related to computer use to the learners. Hopefully, this knowledge helps them to work with computer in safe condition and thence prevent development of WRMSD.